The Great Quadrangle, more popularly known as Tom Quad, is one of the quadrangles of Christ Church, Oxford, England. It is the largest college quad in Oxford, measuring 264 by 261 feet. Although it was begun by Cardinal Wolsey in 1525–1529, he was unable to complete it before his fall from power.

Wolsey planned a cloister, but only the starts of the arches on the walls, and of the supports jutting into the lawn were done; these can still be seen around the quadrangle. The main entrance was also left incomplete, and it is not known how the gatehouse was planned to look. After some 150 years, the gatehouse was completed in 1681–1682 with Tom Tower, designed by Sir Christopher Wren, when John Fell was Dean. It is listed Grade I on the National Heritage List for England. A statue of Queen Anne on Tom Tower overlooks the main entrance to the Quad.