Lymphangitis carcinomatosa is inflammation of the lymph vessels (lymphangitis) caused by a malignancy. Breast, lung, stomach, pancreas, and prostate cancers are the most common tumors that result in lymphangitis. Lymphangitis carcinomatosa was first described by pathologist Gabriel Andral in 1829 in a patient with uterine cancer. Lymphangitis carcinomatosa may show the presence of Kerley B lines on chest X-ray.

Lymphangitis carcinomatosa most often affects people 40–49 years of age.

Lymphangitis carcinomatosa may be caused by the following malignancies as suggested by the mnemonic: "Certain Cancers Spread By Plugging The Lymphatics" (cervical cancer, colon cancer, stomach cancer, breast cancer/bronchiogenic carcinoma, pancreatic cancer, thyroid cancer, laryngeal cancer)