Ball of Fire is a 1941 American screwball comedy film directed by Howard Hawks and starring Gary Cooper and Barbara Stanwyck. This Samuel Goldwyn Productions film (originally distributed by RKO) concerns a group of professors laboring to write an encyclopedia and their encounter with a nightclub performer who provides her own unique knowledge.

The supporting cast includes Oscar Homolka, S. Z. Sakall, Henry Travers, Richard Haydn, Dana Andrews, and Dan Duryea. In 1948, Hawks recycled the plot for a musical film, A Song Is Born, this time starring Danny Kaye and Virginia Mayo. The film is also known as The Professor and the Burlesque Queen. In 2016, the film was deemed "culturally, historically, or aesthetically significant" by the United States Library of Congress, and selected for preservation in its National Film Registry.