syphilitic pemphigus - definition. What is syphilitic pemphigus
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%ما هو (من)٪ 1 - تعريف

CHRONIC BLISTERING SKIN DISEASE
Pemphigus vulgaris, familial; Familial pemphigus vulgaris; Mucosal pemphigus vulgaris; Mucocutaneous pemphigus vulgaris

Pemphigus vulgaris         
Pemphigus vulgaris is a rare chronic blistering skin disease and the most common form of pemphigus. Pemphigus was derived from the Greek word pemphix, meaning blister.
pemphigus         
BLISTERING AUTOIMMUNE DISEASE
Pemphigus, benign familial; Pemphigous; Drug-induced pemphigus; Pemphigoid ocular; Drug induced pemphigus; Pemphigus due to drug; Wild fire pemphigus; NEC pemphigus
['p?mf?g?s]
¦ noun Medicine a skin disease in which watery blisters form on the skin.
Origin
C18: mod. L., from Gk pemphix, pemphig- 'bubble'.
Pemphigus         
BLISTERING AUTOIMMUNE DISEASE
Pemphigus, benign familial; Pemphigous; Drug-induced pemphigus; Pemphigoid ocular; Drug induced pemphigus; Pemphigus due to drug; Wild fire pemphigus; NEC pemphigus
·noun A somewhat rare skin disease, characterized by the development of blebs upon different part of the body.

ويكيبيديا

Pemphigus vulgaris

Pemphigus vulgaris is a rare chronic blistering skin disease and the most common form of pemphigus. Pemphigus was derived from the Greek word pemphix, meaning blister. It is classified as a type II hypersensitivity reaction in which antibodies are formed against desmosomes, components of the skin that function to keep certain layers of skin bound to each other. As desmosomes are attacked, the layers of skin separate and the clinical picture resembles a blister. These blisters are due to acantholysis, or breaking apart of intercellular connections through an autoantibody-mediated response. Over time the condition inevitably progresses without treatment: lesions increase in size and distribution throughout the body, behaving physiologically like a severe burn.

Before the advent of modern treatments, mortality for the disease was close to 90%. Today, the mortality rate with treatment is between 5-15% due to the introduction of corticosteroids as primary treatment. Nevertheless, in 1998, pemphigus vulgaris was the fourth most common cause of death due to a skin disorder. It is thus still deemed "potentially fatal."

The disease mainly affects middle-aged and older adults between 50–60 years old. There has historically been a higher incidence in women.