Lilith Sternin (formerly Sternin-Crane), M.D., Ph.D., Ed.D, A.P.A. is a fictional character on the American television sitcoms Cheers and Frasier, portrayed by Bebe Neuwirth. The character first appears as a date for Frasier Crane, though mutual hostility and discomfort causes the evening to end badly. Several months later, Lilith meets Frasier again and, with some help from Frasier's ex-fiancée, Diane Chambers (Shelley Long), they start a romantic relationship, eventually living together, marrying, and having a son, Frederick.

In the final season of Cheers, Lilith has an affair with another man and leaves Frasier. The affair later unravels and Lilith returns, seeking reconciliation with Frasier. Although Cheers ended ambiguously with regard to Frasier and Lilith's marriage, at the beginning of the spin-off series Frasier, their divorce had been finalized, with Lilith gaining custody of Frederick and remaining in Boston while Frasier has moved back to his hometown of Seattle. Lilith occasionally appears in Frasier, sometimes with Frederick.