androsterone - Definition. Was ist androsterone
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Was (wer) ist androsterone - definition

CHEMICAL COMPOUND

androsterone         
[?andr?(?)'st??r??n, an'dr?st?r??n]
¦ noun Biochemistry a relatively inactive male sex hormone produced by metabolism of testosterone.
1-Androsterone         
1-Androsterone (also known as 1-andro, 1-dehydroepiandrosterone, 1-DHEA, δ1-epiandrosterone, or 5α-androst-1-en-3β-ol-17-one) is a synthetic, orally active anabolic-androgenic steroid (AAS). It is an androgen prohormone of 1-testosterone (dihydroboldenone), 1-androstenedione, and other 1-dehydrogenated androstanes.

Wikipedia

Androsterone

Androsterone, or 3α-hydroxy-5α-androstan-17-one, is an endogenous steroid hormone, neurosteroid, and putative pheromone. It is a weak androgen with a potency that is approximately 1/7 that of testosterone. Androsterone is a metabolite of testosterone and dihydrotestosterone (DHT). In addition, it can be converted back into DHT via 3α-hydroxysteroid dehydrogenase and 17β-hydroxysteroid dehydrogenase, bypassing conventional intermediates such as androstanedione and testosterone, and as such, can be considered to be a metabolic intermediate in its own right.

Androsterone is also known to be an inhibitory androstane neurosteroid, acting as a positive allosteric modulator of the GABAA receptor, and possesses anticonvulsant effects. The unnatural enantiomer of androsterone is more potent as a positive allosteric modulator of GABAA receptors and as an anticonvulsant than the natural form. Androsterone's 3β-isomer is epiandrosterone, and its 5β-epimer is etiocholanolone. The 3β,5β-isomer is epietiocholanolone.

Beispiele aus Textkorpus für androsterone
1. Another sports school in Liaoning provincial capital Shenyang was caught doping students in 2002, while Liaoning distance runner Sun Yingjie was banned for two years after testing positive for the steroid androsterone.