CV/gate (an abbreviation of control voltage/gate) is an analog method of controlling synthesizers, drum machines, and similar equipment with external sequencers. The control voltage typically controls pitch and the gate signal controls note on-off.

This method was widely used in the epoch of analog modular synthesizers and CV/Gate music sequencers, since the introduction of the Roland MC-8 Microcomposer in 1977 through to the 1980s, when it was eventually superseded by the MIDI protocol (introduced in 1983), which is more feature-rich, easier to configure reliably, and more readily supports polyphony. The advent of digital synthesizers also made it possible to store and retrieve voice "patches" – eliminating patch cables and (for the most part) control voltages. However, numerous companies – including Doepfer, who designed a modular system for Kraftwerk in 1992, Buchla, MOTM, Analogue Systems, and others continue to manufacture modular synthesizers that are increasingly popular and rely primarily on analog CV/gate signals for communication. Additionally, some recent non-modular synthesizers (such as the Alesis Andromeda) and many effects devices (including the Moogerfooger pedals by Moog as well as many guitar oriented devices) include CV/gate connectivity. Many modern studios use a hybrid of MIDI and CV/gate to allow synchronization of older and newer equipment.