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Was (wer) ist itch$41177$ - definition
PROTEIN-CODING GENE IN THE SPECIES HOMO SAPIENS
ITCH (biology); ITCH (gene)
Grain itch
SKIN CONDITION CAUSED BY MITES
Barley itch; Mattress itch; Prairie itch; Straw itch; Grain mites; Harvest itch; Cheyletus eruditus; Tyrophagus neiswanderi
Grain itch is a cutaneous condition caused by several types of mites, and characterized by intense pruritus.
Pruritus
![[[Swimmer's itch]]](https://commons.wikimedia.org/wiki/Special:FilePath/CercariaDermatitis.JPG?width=200 "[[Swimmer's itch]]")
![[[Scabies]] is one cause of itching.](https://commons.wikimedia.org/wiki/Special:FilePath/Scabies-burrow.jpg?width=200 "[[Scabies]] is one cause of itching.")
![A [[chipmunk]] scratching itself.](https://commons.wikimedia.org/wiki/Special:FilePath/Squirrel Scratching the Armpit with its Hindlimb.jpg?width=200 "A [[chipmunk]] scratching itself.")
![[[Athlete's foot]] (showing the toes from below plus the front part of the sole)](https://commons.wikimedia.org/wiki/Special:FilePath/Tinea pedis interdigitalis.jpg?width=200 "[[Athlete's foot]] (showing the toes from below plus the front part of the sole)")
SENSATION THAT CAUSES THE DESIRE OR REFLEX TO SCRATCH
Itchiness; Itching; Pruritus; Pruritis; Yeuk; Itch cycle; Pruritic; Skin itch; Anogenital pruritus; Generalised pruritus of unknown aetiology; Methylamphetamine-induced pruritus; Puritis; Itches; Chronic pruritus of unknown origin; Itchy skin
·noun Itching.
itching
SENSATION THAT CAUSES THE DESIRE OR REFLEX TO SCRATCH
Itchiness; Itching; Pruritus; Pruritis; Yeuk; Itch cycle; Pruritic; Skin itch; Anogenital pruritus; Generalised pruritus of unknown aetiology; Methylamphetamine-induced pruritus; Puritis; Itches; Chronic pruritus of unknown origin; Itchy skin
see itch
Wikipedia
ITCH
ITCH is a HECT domain E3 ubiquitin ligase that is ablated in non-agouti-lethal 18H (aka Itchy) mice. Itchy mice develop a severe immunological phenotype after birth that includes hyperplasia of lymphoid and hematopoietic cells, and stomach and lung inflammation. In humans ITCH deficiency causes altered physical growth, craniofacial morphology defects, defective muscle development, and aberrant immune system function. ITCH contains a C2 domain, proline-rich region, WW domains, HECT domain, and multiple amino acids that are phosphorylated and ubiquitinated.
