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Was (wer) ist nucleolus - definition
![Electron micrograph of part of a [[HeLa]] cell. The image is a screen capture from [https://upload.wikimedia.org/wikipedia/commons/1/11/Live-cell-immunogold-labelling-of-RNA-polymerase-II-srep08324-s2.ogv this movie], which shows a Z-stack of the cell.](https://commons.wikimedia.org/wiki/Special:FilePath/NucleolusNCc.jpg?width=200 "Electron micrograph of part of a [[HeLa]] cell. The image is a screen capture from [https://upload.wikimedia.org/wikipedia/commons/1/11/Live-cell-immunogold-labelling-of-RNA-polymerase-II-srep08324-s2.ogv this movie], which shows a Z-stack of the cell.")
Wikipedia
The nucleolus (; PL nucleoli ) is the largest structure in the nucleus of eukaryotic cells. It is best known as the site of ribosome biogenesis, which is the synthesis of ribosomes. The nucleolus also participates in the formation of signal recognition particles and plays a role in the cell's response to stress. Nucleoli are made of proteins, DNA and RNA, and form around specific chromosomal regions called nucleolar organizing regions. Malfunction of nucleoli can be the cause of several human conditions called "nucleolopathies" and the nucleolus is being investigated as a target for cancer chemotherapy.
