2-hydroxy-dATP diphosphatase
CLASS OF ENZYMES
NUDT1; NUDT1 (gene); EC 3.6.1.56; MTH1; MTH2; Oxidized purine nucleoside triphosphatase; (2'-deoxy) ribonucleoside 5'-triphosphate pyrophosphohydrolase; 2-hydroxy-dATP diphosphohydrolase
2-hydroxy-dATP diphosphatase (, also known as oxidized purine nucleoside triphosphatase, or (2'-deoxy) ribonucleoside 5'-triphosphate pyrophosphohydrolase, or Nudix hydrolase 1 (NUDT1), or MutT homolog 1 (MTH1), or 7,8-dihydro-8-oxoguanine triphosphatase) is an enzyme that in humans is encoded by the NUDT1 gene. During DNA repair, the enzyme hydrolyses oxidized purines and prevents their addition onto the DNA chain.