Patch clamp
LABORATORY TECHNIQUE IN ELECTROPHYSIOLOGY USED TO STUDY IONIC CURRENTS IN INDIVIDUAL ISOLATED LIVING CELLS, TISSUE SECTIONS, OR PATCHES OF CELL MEMBRANE
Patch clamp recording; Patch-clamp technique; Patch-clamp; Whole Cell Patch Clamp; Whole-cell patch clamping; Whole-cell patch clamp; Patch clamping; Whole-cell recording; Patch-clamp techniques
The patch clamp technique is a laboratory technique in electrophysiology used to study ionic currents in individual isolated living cells, tissue sections, or patches of cell membrane. The technique is especially useful in the study of excitable cells such as neurons, cardiomyocytes, muscle fibers, and pancreatic beta cells, and can also be applied to the study of bacterial ion channels in specially prepared giant spheroplasts.