Yeast artificial chromosome
GENETICALLY ENGINEERED CHROMOSOME DERIVED FROM THE DNA OF YEAST
Yeast Artificial Chromosome; Chromosomes, artificial, yeast; Yeast artificial chromosomes
Yeast artificial chromosomes (YACs) are genetically engineered chromosomes derived from the DNA of the yeast, Saccharomyces cerevisiae, which is then ligated into a bacterial plasmid. By inserting large fragments of DNA, from 100–1000 kb, the inserted sequences can be cloned and physically mapped using a process called chromosome walking.