Literate programming is a programming paradigm introduced in 1984 by Donald Knuth in which a computer program is given as an explanation of how it works in a natural language, such as English, interspersed (embedded) with snippets of macros and traditional source code, from which compilable source code can be generated. The approach is used in scientific computing and in data science routinely for reproducible research and open access purposes. Literate programming tools are used by millions of programmers today.

The literate programming paradigm, as conceived by Donald Knuth, represents a move away from writing computer programs in the manner and order imposed by the computer, and instead gives programmers macros to develop programs in the order demanded by the logic and flow of their thoughts. Literate programs are written as an exposition of logic in more natural language in which macros are used to hide abstractions and traditional source code, more like the text of an essay.

Literate programming (LP) tools are used to obtain two representations from a source file: one understandable by a compiler or interpreter, the "tangled" code, and another for viewing as formatted documentation, which is said to be "woven" from the literate source. While the first generation of literate programming tools were computer language-specific, the later ones are language-agnostic and exist beyond the individual programming languages.