The Panzerfaust (German: [ˈpantsɐˌfaʊst], lit. "armour fist" or "tank fist", plural: Panzerfäuste) was a development family of single-shot man-portable anti-tank systems developed by Nazi Germany during World War II. The weapons were the first single-use light anti-tank weapons based on a pre-loaded disposable launch tube, a weapon configuration which is still used today (two modern examples being the AT4 and NLAW).

The Panzerfaust-design consisted of a light recoilless launcher tube outfitted with a single pre-loaded high-explosive anti-tank warhead protruding from the muzzle, much like a "fist", hence the name. It was an inexpensive, easy-to-use anti-tank weapon for the common infantry man, being issued as a single unit of ammunition meant to be operated by a single soldier. Firing was done from under the arm at an upward angle as the effective firing range was barely beyond that of hand grenades (30–60 m (98–197 ft) max). After use the launcher was disposed of, much like the safety pin in hand grenades.

Development of the Panzerfaust started in 1942. The initial design was dubbed Faustpatrone (lit. "fist-cartridge") and was smaller than the later designs. Later dubbed Panzerfaust Klein ("tank-fist small"), it entered service in 1943, the larger design being named Panzerfaust Gross ("tank-fist big") and entering service in mid to late 1944. All types saw service with Germany until the end of the war, with the design continuing to see service outside of Germany for a number of years after the war.