Combinatorial Chemistry & High Throughput Screening - meaning and definition. What is Combinatorial Chemistry & High Throughput Screening
Diclib.com
Online Dictionary

What (who) is Combinatorial Chemistry & High Throughput Screening - definition


Combinatorial Chemistry & High Throughput Screening         
Combinatorial Chemistry & High Throughput Screening is a peer-reviewed scientific journal that covers combinatorial chemistry. It was established in 1998 and is published by Bentham Science Publishers.
High-throughput screening         
  • A carousel system to store assay plates for high storage capacity and high speed access
  • A robot arm handles an assay plate
DRUG DISCOVERY EXPERIMENTAL TECHNIQUE
High throughput screening; High throughput drug screening; High throughput screening (HTS); High-throughput screening (HTS); High-throughput experimentation; High-throughput screening assay; Ultra-high-throughput screening; UHTS
High-throughput screening (HTS) is a method for scientific experimentation especially used in drug discovery and relevant to the fields of biology, materials science and chemistry.Inglese J and Auld DS.
Combinatorial chemistry         
  •  Peptides forming in cycles 3 and 4
  • Example of a solid-phase supported dye to signal ligand binding
  • A 27-member tripeptide full library and the three omission libraries. The color circles are amino acids
  • Positional scanning. Full trimer peptide library made from 3 amino acids and its 9 sublibraries. The first row shows the coupling positions
  • Compounds that can be synthesized from solid-phase bound imines
  • Recursive deconvolution. Blue, yellow and red circles: amino acids, Green circle: solid support
  • Flow diagram of the split-mix combinatorial synthesis
  • Use of a solid-supported polyamine to scavenge excess reagent
  • Use of a traceless linker
CHEMICAL METHODS DESIGNED TO RAPIDLY SYNTHESIZE LARGE NUMBERS OF CHEMICAL COMPOUNDS
Combinatorial Chemistry; Combichem; Combinational chemistry; Combinatorial libraries; Combinatorial library; Combinatorial synthesis; High-throughput chemistry; Combinatorial chemistry techniques
Combinatorial chemistry comprises chemical synthetic methods that make it possible to prepare a large number (tens to thousands or even millions) of compounds in a single process. These compound libraries can be made as mixtures, sets of individual compounds or chemical structures generated by computer software.