estradiol - meaning and definition. What is estradiol
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What (who) is estradiol - definition

Oestradiol; 17-beta estradiol; 17 beta estradiol; Estrodiol; 17beta-estradiol; Beta-estradiol; Estradiol-17beta; 17-beta-estradiol; Oestridol; 17β-estradiol; Dihydrotheelin; E2 classical pathway; 17beta-oestradiol; Oestradiol-17beta; 17β-Estradiol; Estrodial; Estradial; Estratrienediol; Estratriendiol; Dihydrofolliculin; Dihydrofolliculine; Dihydroxyestrin; Œstradiol; Free estradiol; Free oestradiol; Estradiol, free; Oestradiol, free
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¦ noun US spelling of oestradiol.
Estradiol dienantate         
Estradiol diheptanoate; Estradiol dienanthate
Estradiol dienanthate (EDE), sold under the brand names Climacteron among others, is a long-acting estrogen medication which was previously used in menopausal hormone therapy for women and to suppress lactation in women. It was formulated in combination with estradiol benzoate (EB), a short-acting estrogen, and testosterone enanthate benzilic acid hydrazone (TEBH), a long-acting androgen/anabolic steroid.
Estradiol palmitate         
Estradiol hexadecanoate; Esmopal; Estradiol monopalmitate; C34H54O3
Estradiol palmitate (brand name Esmopal), or estradiol monopalmitate, also known as estradiol 17β-hexadecanoate, is a naturally occurring steroidal estrogen and an estrogen ester – specifically, the C17β palmitate ester of estradiol. It occurs in the body as a very long-lasting metabolite and prohormone of estradiol.



Estradiol (E2), also spelled oestradiol, is an estrogen steroid hormone and the major female sex hormone. It is involved in the regulation of the estrous and menstrual female reproductive cycles. Estradiol is responsible for the development of female secondary sexual characteristics such as the breasts, widening of the hips and a female-associated pattern of fat distribution. It is also important in the development and maintenance of female reproductive tissues such as the mammary glands, uterus and vagina during puberty, adulthood and pregnancy. It also has important effects in many other tissues including bone, fat, skin, liver, and the brain.

Though estradiol levels in males are much lower than in females, estradiol has important roles in males as well. Apart from humans and other mammals, estradiol is also found in most vertebrates and crustaceans, insects, fish, and other animal species.

Estradiol is produced especially within the follicles of the ovaries, but also in other tissues including the testicles, the adrenal glands, fat, liver, the breasts, and the brain. Estradiol is produced in the body from cholesterol through a series of reactions and intermediates. The major pathway involves the formation of androstenedione, which is then converted by aromatase into estrone and is subsequently converted into estradiol. Alternatively, androstenedione can be converted into testosterone, which can then be converted into estradiol. Upon menopause in females, production of estrogens by the ovaries stops and estradiol levels decrease to very low levels.

In addition to its role as a natural hormone, estradiol is used as a medication, for instance in menopausal hormone therapy and feminizing hormone therapy for transgender women; for information on estradiol as a medication, see the estradiol (medication) article.

Examples of use of estradiol
1. The tablets contain 35 micrograms of ethanol estradiol, the estrogen form standard in oral contraceptives.