excipient - meaning and definition. What is excipient
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What (who) is excipient - definition

SUBSTANCE FORMULATED ALONGSIDE THE ACTIVE INGREDIENT OF A MEDICATION
Excipients; Inactive ingredients; Inactive ingredient; Inert ingredient; Vehicle (pharmaceutics)

excipient         
[?k's?p??nt]
¦ noun an inactive substance that serves as the vehicle or medium for a drug or other active substance.
Origin
C18 (as adjective in the sense 'that takes exception'): from L. excipient-, excipere 'take out'.
Excipient         
·noun An Exceptor.
II. Excipient ·vt Taking an Exception.
III. Excipient ·noun An inert or slightly active substance used in preparing remedies as a vehicle or medium of administration for the medicinal agents.
Excipient         
An excipient is a substance formulated alongside the active ingredient of a medication, included for the purpose of long-term stabilization, bulking up solid formulations that contain potent active ingredients in small amounts (thus often referred to as "bulking agents", "fillers", or "diluents"), or to confer a therapeutic enhancement on the active ingredient in the final dosage form, such as facilitating drug absorption, reducing viscosity, or enhancing solubility. Excipients can also be useful in the manufacturing process, to aid in the handling of the active substance concerns such as by facilitating powder flowability or non-stick properties, in addition to aiding in vitro stability such as prevention of denaturation or aggregation over the expected shelf life.

Wikipedia

Excipient

An excipient is a substance formulated alongside the active ingredient of a medication, included for the purpose of long-term stabilization, bulking up solid formulations that contain potent active ingredients in small amounts (thus often referred to as "bulking agents", "fillers", or "diluents"), or to confer a therapeutic enhancement on the active ingredient in the final dosage form, such as facilitating drug absorption, reducing viscosity, or enhancing solubility. Excipients can also be useful in the manufacturing process, to aid in the handling of the active substance concerns such as by facilitating powder flowability or non-stick properties, in addition to aiding in vitro stability such as prevention of denaturation or aggregation over the expected shelf life. The selection of appropriate excipients also depends upon the route of administration and the dosage form, as well as the active ingredient and other factors. A comprehensive classification system based on structure-property-application relationships has been proposed for excipients used in parenteral medications.

Pharmaceutical regulations and standards require that all ingredients in drugs, as well as their chemical decomposition products, be identified and shown to be safe. Often, more excipient is found in a final drug formulation than active ingredient, and practically all marketed drugs contain excipients.: 1  As with new drug substances and dosage forms thereof, novel excipients themselves can be patented; sometimes, however, a particular formulation involving them is kept as a trade secret instead (if not easily reverse-engineered).