The term express was first applied to hunting rifles and ammunition beginning in the mid-19th century, to indicate a rifle or ammunition capable of higher than typical velocities. The early express cartridges used a heavy charge of black powder to propel a lightweight, often hollow point bullet, at high velocities to maximize point blank range. Later the express cartridges were loaded with nitrocellulose-based gunpowder, leading to the Nitro Express cartridges, the first of which was the .450 Nitro Express.

The term express is still in use today, and is applied to rifles, ammunition, and a type of iron sight. With the widespread adoption of small bore, high velocity rifle cartridges, the meaning of express has shifted in modern usage, and refers to high velocity, large bore rifles and ammunition, typically used for hunting large or dangerous game at close range.