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What (who) is trypsinogen - definition
PRECURSOR FORM (ZYMOGEN) OF TRYPSIN, A DIGESTIVE ENZYME
C39H55N9O17
trypsinogen
[tr?p's?n?d?(?)n]
¦ noun Biochemistry an inactive substance secreted by the pancreas, from which the digestive enzyme trypsin is formed.
Trypsinogen
·noun The antecedent of trypsin, a substance which is contained in the cells of the pancreas and gives rise to the trypsin.
Immunoreactive trypsinogen
USED AS A NEWBORN SCREENING TEST FOR CYSTIC FIBROSIS
Measurement of immunoreactive trypsinogen (IRT) in blood of newborn babies is an assay in rapidly increasing use as a screening test for cystic fibrosis (CF).MedlinePlus Medical Encyclopedia: Neonatal cystic fibrosis screening
Wikipedia
Trypsinogen
Trypsinogen () is the precursor form (or zymogen) of trypsin, a digestive enzyme. It is produced by the pancreas and found in pancreatic juice, along with amylase, lipase, and chymotrypsinogen. It is cleaved to its active form, trypsin, by enteropeptidase, which is found in the intestinal mucosa. Once activated, the trypsin can cleave more trypsinogen into trypsin, a process called autoactivation. Trypsin cleaves the peptide bond on the carboxyl side of basic amino acids such as arginine and lysine.
