Noun
/pisaɪt/
The term "P-site" refers to the peptidyl site in the ribosome that holds the tRNA carrying the growing peptide chain during protein synthesis. It plays a crucial role in translation, where proteins are synthesized based on the genetic information carried by mRNA.
In the context of molecular biology and genetics, "P-site" is commonly used in both oral and written contexts, particularly among professionals and students in these fields. The frequency of use is moderate to high within scientific literature and discussions.
The ribosome has three binding sites for tRNA, including the P-site, where the growing polypeptide chain is located.
➔ Рибосома имеет три связывающих сайта для тРНК, включая P-сайт, где находится растущая полипептидная цепь.
During translation, the tRNA in the P-site donates its amino acid to the chain being synthesized.
➔ В процессе трансляции тРНК на P-сайте передает свою аминокислоту синтезируемой цепи.
The interaction at the P-site is crucial for the efficiency of protein synthesis.
➔ Взаимодействие на P-сайте имеет ключевое значение для эффективности синтеза белка.
The term "P-site" itself is not commonly featured in idiomatic expressions; however, it is tightly linked to various scientific concepts that involve synthesis and mechanisms of function within biological systems. Here are a few relevant scientific idioms and phrases that highlight the importance of biological processes, including the P-site:
The drug needs to be delivered directly to the site of action to be effective.
➔ Лекарство должно быть доставлено непосредственно к месту действия, чтобы быть эффективным.
On the molecular level
Scientists study interactions on the molecular level, including the role of the P-site in ribosomes.
➔ Ученые изучают взаимодействия на молекулярном уровне, включая роль P-сайта в рибосомах.
Chain of events
The term "P-site" is derived from the word "peptidyl", which refers to the part of the tRNA that is linked to the growing peptide chain during protein synthesis. The designation 'P' signifies its position in the ribosome relative to the A (aminoacyl) site and E (exit) site.
Synonyms: - Peptidyl binding site - Peptide site
Antonyms: - None specifically applicable, as "P-site" is a technical term within a precise scientific context.
Thus, "P-site" is a specialized term rooted deeply in the biological sciences, particularly in the study of genetics and protein synthesis. Its significance in the translation process highlights the intricate mechanisms of life at a molecular level.