pre-B-cell cloning assay (english) - meaning, definition, translation, pronunciation

Part of Speech

Noun

Phonetic Transcription

/prɪ ˌbiː ˈsɛl ˈkloʊnɪŋ əˈseɪ/

Meaning and Use

The "pre-B-cell cloning assay" is a laboratory technique used to assess the survival, proliferation, and differentiation of pre-B-cells, which are a stage in the development of B-cells in the immune system. It is commonly used in immunological research to study the development and function of B-cell precursors and their response to various stimuli.

This term is frequent within scientific literature, especially in contexts related to immunology and cell biology. Its usage is more prevalent in written contexts, such as academic papers, articles, and textbooks, given its technical nature and specificity.

Example Sentences

1. The researchers conducted a pre-B-cell cloning assay to determine the effects of cytokines on B-cell development.

2. Исследователи провели пробу на клонирование предшественников B-клеток, чтобы определить влияние цитокинов на развитие B-клеток.

3. The results from the pre-B-cell cloning assay indicated a significant increase in cell proliferation in the presence of IL-7.

4. Результаты пробы на клонирование предшественников B-клеток показали значительное увеличение пролиферации клеток в присутствии IL-7.

5. Utilizing a pre-B-cell cloning assay allowed us to better understand the signaling pathways involved in B-cell maturation.

6. Использование пробы на клонирование предшественников B-клеток позволило нам лучше понять сигнальные пути, участвующие в созревании B-клеток.

Idiomatic Expressions

The term "pre-B-cell" in itself may not frequently appear in idiomatic expressions, largely due to its specificity. However, it relates to broader immunological contexts. Here are some idiomatic expressions involving the B-cell context:

1. "B-cell maturation" - This refers to the process by which immature B-cells become fully functional.
2. The study provided insight into B-cell maturation during immune responses.

3. Исследование дало представление о созревании B-клеток во время иммунных реакций.

4. "B-cell activation" - Describes the process by which B-cells are stimulated to respond to pathogens.

5. The vaccine was designed to enhance B-cell activation against the virus.

6. Вакцина была разработана для повышения активации B-клеток против вируса.

7. "B-cell receptor signaling" - This involves the pathways activated by the binding of antigens to the B-cell receptor.

8. Understanding B-cell receptor signaling is crucial for developing targeted therapies.
9. Понимание сигнальной передачи рецепторов B-клеток имеет решающее значение для разработки целевых терапий.

Etymology

The term "pre-B-cell" comes from the prefix "pre-" indicating a developmental stage that occurs before the full formation of B-cells. The "B-cell" part refers to a type of white blood cell crucial for the adaptive immune response, derived from the bone marrow and named for the bursa of Fabricius in birds, where B-cells were first discovered to mature.

Synonyms and Antonyms

Synonyms

• Pre-B-lymphocyte assay
• Pre-B-cell development assay

Antonyms

• Post-B-cell assay
• Mature B-cell assay

This detailed breakdown of "pre-B-cell cloning assay" covers its meaning, usage, and related concepts adequately, placing it well within the realm of scientific discourse.