preferred binding site (english) - meaning, definition, translation, pronunciation

Part of Speech

• Noun Phrase

Phonetic Transcription

• /prɪˈfɜrdɪd ˈbaɪndɪŋ saɪt/

Meaning and Usage

The phrase "preferred binding site" refers to a specific location on a molecule (often a protein or a receptor) where a ligand, such as a drug or other substance, preferentially attaches. This term is commonly used in biochemistry, pharmacology, and molecular biology, where understanding the interactions between molecules is crucial for drug design and therapeutic interventions.

The frequency of use is relatively high in scientific literature and in discussions related to drug action mechanisms, reducing in casual speech. It is predominantly used in written contexts, particularly in academic and research texts.

Example Sentences

1. The researcher identified the preferred binding site of the enzyme for the substrate.
   (Исследователь определил предпочитаемый сайт связывания фермента для субстрата.)

2. By modifying the compound, scientists could enhance its affinity for the preferred binding site in the target protein.
   (Изменив соединение, ученые могли увеличить его сродство к предпочитаемому сайту связывания в целевом белке.)

3. Determining the preferred binding site was essential for the development of the new drug.
   (Определение предпочитаемого сайта связывания было важным для разработки нового лекарства.)

Idiomatic Expressions

The phrase "preferred binding site" is less likely to appear in idiomatic expressions, as it is mainly technical language. However, here are some phrases where "binding" and "site" might be relevant in more idiomatic usage:

1. "Find common ground" often refers to a binding agreement between parties to ensure cooperation.
   (Найти общую почву часто относится к связывающему соглашению между сторонами для обеспечения сотрудничества.)

2. "At the site of action" describes a location where an event occurs, similar to where a drug has its effects.
   (На месте действия описывает местонахождение, где происходит событие, аналогично тому, где лекарство оказывает свои эффекты.)

3. "Binding agreement" is a term describing a contract or deal that is legally enforceable.
   (Связывающее соглашение — это термин, описывающий контракт или сделку, которая имеет юридическую силу.)

Etymology

• "Preferred": Derived from the Latin word "praeferre," meaning to carry in front of or to value more.
• "Binding": Comes from the Old English "bindan," meaning to tie or fasten.
• "Site": From the Latin word "situs," meaning position or locality.

Synonyms and Antonyms

Synonyms: - Preferred attachment location - Favorable binding position

Antonyms: - Unfavorable binding site - Non-preferred interaction location