Science and technology in the United States has a long history, producing many important figures and developments in the field. The United States of America came into being around the Age of Enlightenment (1685 to 1815), an era in Western philosophy in which writers and thinkers, rejecting the perceived superstitions of the past, instead chose to emphasize the intellectual, scientific and cultural life, centered upon the 18th century, in which reason was advocated as the primary source for legitimacy and authority. Enlightenment philosophers envisioned a "republic of science," where ideas would be exchanged freely and useful knowledge would improve the lot of all citizens.

The United States Constitution itself reflects the desire to encourage scientific creativity. It gives the United States Congress the power "to promote the progress of science and useful arts, by securing for limited times to authors and inventors the exclusive right to their respective writings and discoveries." This clause formed the basis for the U.S. patent and copyright systems, whereby creators of original art and technology would get a government granted monopoly, which after a limited period would become free to all citizens, thereby enriching the public domain.