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4.50 from Paddington is a detective fiction novel by Agatha Christie, first published in November 1957 in the United Kingdom by Collins Crime Club. This work was published in the United States at the same time as What Mrs. McGillicuddy Saw!, by Dodd, Mead. The novel was published in serial form before the book was released in each nation, and under different titles. The US edition retailed at $2.95.
Reviewers at the time of publication generally liked the novel, but would have liked more direct involvement of Miss Marple, and less consideration of her failing strength, using others to act for her. A later review by Barnard found the story short on clues, but favourably noted Lucy Eyelesbarrow as an independent woman character.
The 1961 film Murder, She Said was based on this novel as were several television programmes.