5-HT2C receptor agonist - significado y definición. Qué es 5-HT2C receptor agonist
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Qué (quién) es 5-HT2C receptor agonist - definición


5-HT2C receptor agonist         
  • '''Figure 1 – Mechanism of action.''' A hypothetical model for the agonist activation of 5-HT<sub>2C</sub> receptor. Activation leads to accumulation of inositol phosphate and increase in intracellular Ca<sup>2+</sup>. Receptor activation also stimulates the ERK pathway and RhoA/PLD pathway.
  • '''Figure 6. [[Lorcaserin]]'''    ((1R)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine).
  • '''Figure 4.''' The best fit mapped with the four features of the pharmacophore.
  • '''Figure 3.''' Outline of the 5-HT<sub>2C</sub> receptor. The most important contacts when serotonin binds are with residues in TM helixes 3, 5, and 6.
  • '''Figure 2.''' A schematic representation of the two state-model in which the 5-HT<sub>2C</sub> receptor are in equilibrium between an active state (R*) and an inactive state (R).
ENDOGENOUS COMPOUNDS AND DRUGS THAT SPECIFICALLY STIMULATE SEROTONIN 5-HT2 RECEPTORS. INCLUDED UNDER THIS HEADING ARE AGONISTS FOR ONE OR MORE OF THE SPECIFIC 5-HT2 RECEPTOR SUBTYPES
5-HT2C receptor agonists; Wikipedia talk:Articles for creation/5-HT2c receptor agonist; 5-HT2c receptor agonist
5-HT2C receptor agonists are a class of drugs that activate 5-HT2C receptors. They have been investigated for the treatment of a number of conditions including obesity, psychiatric disorders, sexual dysfunction and urinary incontinence.
5-HT2C receptor         
PROTEIN-CODING GENE IN THE SPECIES HOMO SAPIENS
HTR2C; 5-HT receptor 2C; 5HT2C receptor; 5-HT2C; 5-HT1C; 5-HT1C receptor; HTR2C (gene)
The 5-HT2C receptor is a subtype of 5-HT receptor that binds the endogenous neurotransmitter serotonin (5-hydroxytryptamine, 5-HT). It is a G protein-coupled receptor (GPCR) that is coupled to Gq/G11 and mediates excitatory neurotransmission.
Adrenergic agonist         
DRUG THAT STIMULATES A RESPONSE FROM THE ADRENERGIC RECEPTORS
Adrenergics; Adrenergic agonists; Β-receptor antagonist; B-receptor antagonist; Adrenergic receptor agonists; Adrenergic receptor agonist; Α2-adrenergic agonist
An adrenergic agonist is a drug that stimulates a response from the adrenergic receptors. The five main categories of adrenergic receptors are: α1, α2, β1, β2, and β3, although there are more subtypes, and agonists vary in specificity between these receptors, and may be classified respectively.