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The Pontifical Biblical Commission (Latin: Pontificia Commissio Biblica) is a pontifical commission established within the Roman Curia to ensure the proper interpretation and defense of the Bible.
Since 1988, it has been closely attached to the Congregation for the Doctrine of the Faith, whose prefect heads the Commission. In March 2022, Pope Francis reaffirmed that relationship with his apostolic constitution Praedicate evangelium, effective 5 June 2022, even as it changed the Congregation's name to the Dicastery for the Doctrine of the Faith.