Newberry Volcano is a large active shield-shaped stratovolcano located about 20 miles (32 km) south of Bend, Oregon, United States, 35 miles (56 km) east of the major crest of the Cascade Range, within the Newberry National Volcanic Monument. Its highest point is Paulina Peak. The largest volcano in the Cascade Volcanic Arc, Newberry has an area of 1,200 square miles (3,100 km²) when its lava flows are taken into account. From north to south, the volcano has a length of 75 miles (121 km), with a width of 27 miles (43 km) and a total volume of approximately 120 cubic miles (500 km³). It was named for the geologist and surgeon John Strong Newberry, who explored central Oregon for the Pacific Railroad Surveys in 1855. The surrounding area has been inhabited by Native American populations for more than 10,000 years.

The volcano contains a large caldera, 4 by 5 miles (6.4 km × 8.0 km) in diameter, known as the Newberry Caldera. Within the caldera are two lakes: Paulina Lake and East Lake. The volcano and its vicinity include many pyroclastic cones, lava flows and lava domes; Newberry has more than 400 vents, the most of any volcano in the contiguous United States. Glaciers may have once been present at the volcano, though this remains contested. The area has a dry climate with low precipitation levels and little surface runoff.

The origin of the volcano remains somewhat unclear; while some scientists believe it originated from an independent hotspot, most evidence indicates that it formed from the subduction of the oceanic Juan de Fuca and Gorda tectonic plates under the continental North American Plate. Eruptive activity at Newberry Volcano began about 600,000 years ago and has continued into the Holocene, the last eruption taking place 1,300 years ago. Unlike other shield-shaped volcanoes, which often erupt basaltic lavas only, Newberry Volcano has also erupted andesitic and rhyolitic lavas. A popular destination for hiking, fishing, boating, and other recreational activities, the volcano lies within 19 miles (31 km) of 16,400 people and within 62 miles (100 km) of nearly 200,000 people, and it continues to pose a threat to life. Still considered an active volcano, it could erupt and produce lava flows, pyroclastic flows, lahars (volcanically induced mudslides, landslides, and debris flows), ashfall, earthquakes, avalanches, and floods. To track this threat, the volcano and its surroundings are closely monitored with sensors by the United States Geological Survey.