UDP-glucose 4-epimerase
CLASS OF ENZYMES
GALE; UDP galactose epimerase; UDPgalactose-4-epimerase; Galactose epimerase; EC 5.1.3.2; UDP-alpha-D-glucose 4-epimerase
The enzyme UDP-glucose 4-epimerase (), also known as UDP-galactose 4-epimerase or GALE, is a homodimeric epimerase found in bacterial, fungal, plant, and mammalian cells. This enzyme performs the final step in the Leloir pathway of galactose metabolism, catalyzing the reversible conversion of UDP-galactose to UDP-glucose.