liposome - significado y definición. Qué es liposome
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Qué (quién) es liposome - definición

COMPOSITE STRUCTURES MADE LARGELY OF PHOSPHOLIPIDS
Liposomes; Escheriosome; Liposomal; Lipid shell; Banghasome
  • Pictorial representation of targeted theranostics liposomal delivery
  • Various types of phosphatidylcholine liposomes in suspension. Method of [[phase-contrast microscopy]] (1000-fold magnification).   The following types of liposomes are visible: small monolamellar vesicles, large monolamellar vesicles, multilamellar vesicles, oligolamellar vesicles.
  • fluorescence]] microscopy (1250-fold magnification).

liposome         
['l?p?s??m, 'l??-]
¦ noun Biochemistry a minute artificial spherical sac of phospholipid molecules enclosing a water droplet, used to carry drugs or other substances into the tissues.
Cationic liposome         
  • Mechanisms of CME, CavME, and macropinocytosis. These endocytic pathways are all common in the delivery of nucleic acids from lamellar cationic liposomes.
Cationic liposomes are spherical structures that contain positively charged lipids. Cationic liposomes can vary in size between 40 nm and 500 nm, and they can either have one lipid bilayer (monolamellar) or multiple lipid bilayers (multilamellar).
Unilamellar liposome         
A unilamellar liposome is a spherical chamber/vesicle, bounded by a single bilayer of an amphiphilic lipid or a mixture of such lipids, containing aqueous solution inside the chamber. Unilamellar liposomes are used to study biological systems and to mimic cell membranes, and are classified into three groups based on their size: small unilamellar liposomes/vesicles (SUVs) that with a size range of 20–100 nm, large unilamellar liposomes/vesicles (LUVs) with a size range of 100–1000 nm and giant unilamellar liposomes/vesicles (GUVs) with a size range of 1-200 µm.

Wikipedia

Liposome

A liposome is a small artificial vesicle, spherical in shape, having at least one lipid bilayer. Due to their hydrophobicity and/or hydrophilicity, biocompatibility, particle size and many other properties, liposomes can be used as drug delivery vehicles for administration of pharmaceutical drugs and nutrients, such as lipid nanoparticles in mRNA vaccines, and DNA vaccines. Liposomes can be prepared by disrupting biological membranes (such as by sonication).

Liposomes are most often composed of phospholipids, especially phosphatidylcholine and cholesterol, but may also include other lipids, such as egg, phosphatidylethanolamine, as long as they are compatible with lipid bilayer structure. A liposome design may employ surface ligands for attaching to unhealthy tissue.

The major types of liposomes are the multilamellar vesicle (MLV, with several lamellar phase lipid bilayers), the small unilamellar liposome vesicle (SUV, with one lipid bilayer), the large unilamellar vesicle (LUV), and the cochleate vesicle. A less desirable form are multivesicular liposomes in which one vesicle contains one or more smaller vesicles.

Liposomes should not be confused with lysosomes, or with micelles and reverse micelles composed of monolayers.