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Qu'est-ce (qui) est mutation$51061$ - définition

EQUILIBRIUM IN THE NUMBER OF DELETERIOUS ALLELES IN A POPULATION
Mutation selection balance; Selection-mutation balance; Mutation-selection balance

mutate         
  • date=31 December 2015 }}</ref>
  • Five types of chromosomal mutations
  • fitness]] of each mutant was compared with the ancestral type. A fitness of zero, less than one, one, more than one, respectively, indicates that mutations are lethal, deleterious, neutral, and advantageous.<ref name="Sanjuán04" />
  • A red [[tulip]] exhibiting a partially yellow petal due to a mutation in its genes
  • Types of small-scale mutations
  • This figure shows a simplified version of loss-of-function, switch-of-function, gain-of-function, and conservation-of-function mutations.
  • translational]] regulation of [[gene expression]].
  • Selection of disease-causing mutations, in a standard table of the [[genetic code]] of [[amino acid]]s<ref>References for the image are found in Wikimedia Commons page at: [[Commons:File:Notable mutations.svg#References]].</ref>
  • Point mutations classified by impact on protein
  • somatic]] mutation that may also be passed on in the [[germline]].
  • ''[[Prodryas persephone]]'', a Late [[Eocene]] butterfly
  • Mutation with double bloom in the Langheck Nature Reserve near [[Nittel]], Germany
CHANGE OF THE NUCLEOTIDE SEQUENCE OF THE GENOME OF AN ORGANISM
Mutations; Genetic mutation; Mutates; Mutate; Mutation and disease; Gene mutation; Loss-of-function mutation; Gain-of-function mutation; Neomorphic mutation; Antimorphic mutation; Amorphic mutation; Loss-of-function; Mutant allele; Genetic mutations; Conditional lethal mutation; Conditional mutation; Mutation event; Loss of function; Mutated; Spontaneous mutation; Mutant proteins; Nuclear mutation; Reversion (genetics); Genetic damage; DNA mutations; Chromosomal gain; Beneficial mutation; Acquired genetic mutation; Reverse mutation; Genetic changes; Mutating; Viral mutation; Backmutation; Back-mutation; Gene mutation analysis; Extragenic; Radiation genetics; Mutant Proteins; DNA error; In-frame mutation; In-frame deletion; DNA mutation; Mutational; Distribution of fitness effects; Types of mutation; Sporadic mutation; Harmful mutation; Deleterious mutation; Sport (genetics); Mutation (biology); Inactivating mutation; De novo mutations; Activating mutations; Mutant spectrum; Deformation (biology); Loss-of-function mutant; Gain of function mutation; Substitution (genetics); Loss of function mutation
¦ verb undergo or cause to undergo mutation.
Derivatives
mutative adjective
mutator noun
Origin
C19: back-form. from mutation.
mutation         
  • date=31 December 2015 }}</ref>
  • Five types of chromosomal mutations
  • fitness]] of each mutant was compared with the ancestral type. A fitness of zero, less than one, one, more than one, respectively, indicates that mutations are lethal, deleterious, neutral, and advantageous.<ref name="Sanjuán04" />
  • A red [[tulip]] exhibiting a partially yellow petal due to a mutation in its genes
  • Types of small-scale mutations
  • This figure shows a simplified version of loss-of-function, switch-of-function, gain-of-function, and conservation-of-function mutations.
  • translational]] regulation of [[gene expression]].
  • Selection of disease-causing mutations, in a standard table of the [[genetic code]] of [[amino acid]]s<ref>References for the image are found in Wikimedia Commons page at: [[Commons:File:Notable mutations.svg#References]].</ref>
  • Point mutations classified by impact on protein
  • somatic]] mutation that may also be passed on in the [[germline]].
  • ''[[Prodryas persephone]]'', a Late [[Eocene]] butterfly
  • Mutation with double bloom in the Langheck Nature Reserve near [[Nittel]], Germany
CHANGE OF THE NUCLEOTIDE SEQUENCE OF THE GENOME OF AN ORGANISM
Mutations; Genetic mutation; Mutates; Mutate; Mutation and disease; Gene mutation; Loss-of-function mutation; Gain-of-function mutation; Neomorphic mutation; Antimorphic mutation; Amorphic mutation; Loss-of-function; Mutant allele; Genetic mutations; Conditional lethal mutation; Conditional mutation; Mutation event; Loss of function; Mutated; Spontaneous mutation; Mutant proteins; Nuclear mutation; Reversion (genetics); Genetic damage; DNA mutations; Chromosomal gain; Beneficial mutation; Acquired genetic mutation; Reverse mutation; Genetic changes; Mutating; Viral mutation; Backmutation; Back-mutation; Gene mutation analysis; Extragenic; Radiation genetics; Mutant Proteins; DNA error; In-frame mutation; In-frame deletion; DNA mutation; Mutational; Distribution of fitness effects; Types of mutation; Sporadic mutation; Harmful mutation; Deleterious mutation; Sport (genetics); Mutation (biology); Inactivating mutation; De novo mutations; Activating mutations; Mutant spectrum; Deformation (biology); Loss-of-function mutant; Gain of function mutation; Substitution (genetics); Loss of function mutation
¦ noun
1. the action or process of changing in form or nature.
a change.
2. a change in the structure of a gene resulting in a variant form which may be transmitted to subsequent generations.
a distinct form resulting from genetic mutation.
3. Linguistics (in Celtic languages) change of an initial consonant in a word caused by the preceding word.
(in Germanic languages) the umlaut process.
Derivatives
mutational adjective
mutationally adverb
Origin
ME: from L. mutatio(n-), from mutare 'to change'.
mutation         
  • date=31 December 2015 }}</ref>
  • Five types of chromosomal mutations
  • fitness]] of each mutant was compared with the ancestral type. A fitness of zero, less than one, one, more than one, respectively, indicates that mutations are lethal, deleterious, neutral, and advantageous.<ref name="Sanjuán04" />
  • A red [[tulip]] exhibiting a partially yellow petal due to a mutation in its genes
  • Types of small-scale mutations
  • This figure shows a simplified version of loss-of-function, switch-of-function, gain-of-function, and conservation-of-function mutations.
  • translational]] regulation of [[gene expression]].
  • Selection of disease-causing mutations, in a standard table of the [[genetic code]] of [[amino acid]]s<ref>References for the image are found in Wikimedia Commons page at: [[Commons:File:Notable mutations.svg#References]].</ref>
  • Point mutations classified by impact on protein
  • somatic]] mutation that may also be passed on in the [[germline]].
  • ''[[Prodryas persephone]]'', a Late [[Eocene]] butterfly
  • Mutation with double bloom in the Langheck Nature Reserve near [[Nittel]], Germany
CHANGE OF THE NUCLEOTIDE SEQUENCE OF THE GENOME OF AN ORGANISM
Mutations; Genetic mutation; Mutates; Mutate; Mutation and disease; Gene mutation; Loss-of-function mutation; Gain-of-function mutation; Neomorphic mutation; Antimorphic mutation; Amorphic mutation; Loss-of-function; Mutant allele; Genetic mutations; Conditional lethal mutation; Conditional mutation; Mutation event; Loss of function; Mutated; Spontaneous mutation; Mutant proteins; Nuclear mutation; Reversion (genetics); Genetic damage; DNA mutations; Chromosomal gain; Beneficial mutation; Acquired genetic mutation; Reverse mutation; Genetic changes; Mutating; Viral mutation; Backmutation; Back-mutation; Gene mutation analysis; Extragenic; Radiation genetics; Mutant Proteins; DNA error; In-frame mutation; In-frame deletion; DNA mutation; Mutational; Distribution of fitness effects; Types of mutation; Sporadic mutation; Harmful mutation; Deleterious mutation; Sport (genetics); Mutation (biology); Inactivating mutation; De novo mutations; Activating mutations; Mutant spectrum; Deformation (biology); Loss-of-function mutant; Gain of function mutation; Substitution (genetics); Loss of function mutation
n.
1) to induce a mutation
2) a gene mutation

Wikipédia

Mutation–selection balance

Mutation–selection balance is an equilibrium in the number of deleterious alleles in a population that occurs when the rate at which deleterious alleles are created by mutation equals the rate at which deleterious alleles are eliminated by selection. The majority of genetic mutations are neutral or deleterious; beneficial mutations are relatively rare. The resulting influx of deleterious mutations into a population over time is counteracted by negative selection, which acts to purge deleterious mutations. Setting aside other factors (e.g., balancing selection, and genetic drift), the equilibrium number of deleterious alleles is then determined by a balance between the deleterious mutation rate and the rate at which selection purges those mutations.

Mutation–selection balance was originally proposed to explain how genetic variation is maintained in populations, although several other ways for deleterious mutations to persist are now recognized, notably balancing selection. Nevertheless, the concept is still widely used in evolutionary genetics, e.g. to explain the persistence of deleterious alleles as in the case of spinal muscular atrophy, or, in theoretical models, mutation-selection balance can appear in a variety of ways and has even been applied to beneficial mutations (i.e. balance between selective loss of variation and creation of variation by beneficial mutations).