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Qu'est-ce (qui) est psoralen - définition

CHEMICAL COMPOUND

Psoralens

psoralen

['s?:r?l?n]

¦ noun Chemistry any of a group of cyclic compounds present in certain plants, used to treat psoriasis and other skin disorders.

Origin

1930s: from mod. L. Psoralea (former plant genus name), from Gk psoraleos 'itchy' (from psora 'itch') + the suffix -en (cf. -ene).

PUVA therapy

ULTRAVIOLET LIGHT THERAPY TREATMENT

Puva therapy; PUVA; Psoralen and ultraviolet A therapy; Psoralen plus ultraviolet A; Narrowband UVB therapy; Psoralen and ultraviolet A phototherapy

PUVA (psoralen and UVA) is an ultraviolet light therapy treatment for skin diseases: eczema, psoriasis, graft-versus-host disease, vitiligo, mycosis fungoides, large plaque parapsoriasis, and cutaneous T-cell lymphoma, using the sensitizing effects of the drug psoralen. The psoralen is applied or taken orally to sensitize the skin, then the skin is exposed to UVA.

https://en.wikipedia.org/wiki/PUVA_therapy

Wikipédia

Psoralen

Psoralen (also called psoralene) is the parent compound in a family of naturally occurring organic compounds known as the linear furanocoumarins. It is structurally related to coumarin by the addition of a fused furan ring, and may be considered as a derivative of umbelliferone. Psoralen occurs naturally in the seeds of Psoralea corylifolia, as well as in the common fig, celery, parsley, West Indian satinwood, and in all citrus fruits. It is widely used in PUVA (psoralen + UVA) treatment for psoriasis, eczema, vitiligo, and cutaneous T-cell lymphoma; these applications are typically through the use of medications such as Methoxsalen. Many furanocoumarins are extremely toxic to fish, and some are deposited in streams in Indonesia to catch fish.

https://en.wikipedia.org/wiki/Psoralen