Formula One, abbreviated to F1, is the highest class of open-wheeled auto racing defined by the Fédération Internationale de l'Automobile (FIA), motorsport's world governing body. The "formula" in the name refers to a set of rules to which all participants and cars must conform. Each year, the F1 World Championship season is held. It consists of a series of races, known as Grands Prix, held usually on purpose-built circuits, and in a few cases on closed city streets. Drivers are awarded points based on their finishing position in each race, and the driver who accumulates the most points over each championship is crowned that year's World Drivers' Champion. As of the 2023 Australian Grand Prix, there have been 774 Formula One drivers from 41 different nationalities who have raced at least one of the 1,082 FIA World Championship races since the first such event, the 1950 British Grand Prix.

Seven-time champions Michael Schumacher and Lewis Hamilton hold the record for the most championships. Hamilton also holds the record for the most wins with 103, the most pole positions with 103, the most points with 4443.5, and the most podiums with 192. Fernando Alonso has entered more Grands Prix than anyone else (361) and also holds the record for the most Grand Prix starts (358). The United Kingdom is the most represented country, having produced 163 drivers. Ten countries have been represented by just one. China became the latest country to be represented by a driver when Zhou Guanyu made his Formula One debut at the 2022 Bahrain Grand Prix driving for Alfa Romeo. The most recent drivers to make their Formula One debut are Oscar Piastri and Logan Sargeant, who debuted at the 2023 Bahrain Grand Prix.

This list includes all drivers who have entered a World Championship race, including participants of the Indianapolis 500 between 1950 and 1960 when it was part of the World Championship (although not being run according to Formula One rules).