Vertaling en analyse van woorden door kunstmatige intelligentie ChatGPT
Op deze pagina kunt u een gedetailleerde analyse krijgen van een woord of zin, geproduceerd met behulp van de beste kunstmatige intelligentietechnologie tot nu toe:
- hoe het woord wordt gebruikt
- gebruiksfrequentie
- het wordt vaker gebruikt in mondelinge of schriftelijke toespraken
- opties voor woordvertaling
- Gebruiksvoorbeelden (meerdere zinnen met vertaling)
- etymologie
Wat (wie) is purine-; 5"; -nucleotidase - definitie
![The main purine-derived [[nucleobase]]s.](https://commons.wikimedia.org/wiki/Special:FilePath/Blausen 0323 DNA Purines.png?width=200 "The main purine-derived [[nucleobase]]s.")
Wikipedia
5′-Nucleotidase (EC 3.1.3.5) is an enzyme which catalyzes the phosphorylytic cleavage of 5′-nucleotides. Although originally found in snake venom, the activity of 5'nucleotidase has been described for bacteria and plant cells, and is widely distributed in vertebrate tissue. In mammalian cells the enzyme is predominantly located in the plasma membrane and its primary role is in the conversion of extracellular nucleotides (e.g. 5'-AMP), which are generally impermeable, to the corresponding nucleoside (e.g. adenosine) which can readily enter most cells. Consequently, the enzyme plays a key role in the metabolism of nucleotides.
The enzyme has a wide substrate specificity for nucleotides and has been shown to hydrolyze 5'nucleotides rapidly, ribose-5-phosphate slowly, and other phosphate esters extremely slowly (if at all).
The enzyme catalyses the following reaction:
- a 5′-nucleotide + H2O ⇌ a nucleoside + phosphate
The 5′-nucleotidase-catalyzed reaction of an AMP nucleotide to adenosine nucleoside is shown below:
