The Institute of Noetic Sciences (IONS) is an American non-profit parapsychological research institute. It was co-founded in 1973 by former astronaut Edgar Mitchell, the sixth man to walk on the Moon, along with investor Paul N. Temple and others interested in purported paranormal phenomena, in order to encourage and conduct research on noetics and human potentials.

The Institute conducts research on topics such as spontaneous remission, meditation, consciousness, alternative healing practices, consciousness-based healthcare, spirituality, human potential, psychic abilities, psychokinesis and survival of consciousness after bodily death. The Institute maintains a free database, available on the Internet, with citations to more than 6,500 articles about whether physical and mental health benefits might be connected to meditation and yoga.

Headquartered outside Petaluma, California, the IONS is situated on a 200-acre (81 ha) campus that includes offices, a research laboratory and a retreat center (originally the campus of World College West). Its current director is Claire Lachance. Other researchers associated with it include Dean Radin and Rupert Sheldrake.