The pyroxenes (commonly abbreviated to Px) are a group of important rock-forming inosilicate minerals found in many igneous and metamorphic rocks. Pyroxenes have the general formula XY(Si,Al)₂O₆, where X represents calcium (Ca), sodium (Na), iron (Fe II) or magnesium (Mg) and more rarely zinc, manganese or lithium, and Y represents ions of smaller size, such as chromium (Cr), aluminium (Al), magnesium (Mg), cobalt (Co), manganese (Mn), scandium (Sc), titanium (Ti), vanadium (V) or even iron (Fe II or Fe III). Although aluminium substitutes extensively for silicon in silicates such as feldspars and amphiboles, the substitution occurs only to a limited extent in most pyroxenes. They share a common structure consisting of single chains of silica tetrahedra. Pyroxenes that crystallize in the monoclinic system are known as clinopyroxenes and those that crystallize in the orthorhombic system are known as orthopyroxenes.

The name pyroxene is derived from the Ancient Greek words for 'fire' (pyr πυρ) and 'stranger' (ksénos ξένος). Pyroxenes were so named because of their presence in volcanic lavas, where they are sometimes found as crystals embedded in volcanic glass; it was assumed they were impurities in the glass, hence the name meaning 'fire-strangers'. However, they are simply early-forming minerals that crystallized before the lava erupted.

The upper mantle of Earth is composed mainly of olivine and pyroxene minerals. Pyroxene and feldspar are the major minerals in basalt, andesite, and gabbro rocks.