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Что (кто) такое 5α-Reductase - определение
5α-Reductase
![[[Steroidogenesis]], showing both actions of 5α-reductase at bottom center.](https://commons.wikimedia.org/wiki/Special:FilePath/Steroidogenesis.svg?width=200 "[[Steroidogenesis]], showing both actions of 5α-reductase at bottom center.")
![[[Testosterone]]](https://commons.wikimedia.org/wiki/Special:FilePath/Testosteron.svg?width=200 "[[Testosterone]]")
![[[Dihydrotestosterone]]](https://commons.wikimedia.org/wiki/Special:FilePath/Androstanolone.svg?width=200 "[[Dihydrotestosterone]]")
ENZYME FAMILY
5 alpha reductase; 5-alpha-reductase; 3-oxo-5a-steroid 4-dehydrogenase; 5 alpha-reductase; 5α-reductase; 3-oxo-5alpha-steroid 4-dehydrogenase; 5a-reductase; 5aReductase; Testosterone 5-alpha-Reductase; 5A-Reductase; 5α-reductase type 2; 5 a Reductase; 5-Alpha reductase; 5AR; EC 1.3.99.5; 3-oxo-5alpha-steroid:acceptor Delta4-oxidoreductase; 5-alpha reductase
5α-Reductases, also known as 3-oxo-5α-steroid 4-dehydrogenases, are enzymes involved in steroid metabolism. They participate in three metabolic pathways: bile acid biosynthesis, androgen and estrogen metabolism.
5α-Reductase 2 deficiency
MEDICAL CONDITION
5-alpha-reductase deficency; 5 alpha reductase deficiency; Pseudovaginal perineoscrotal hypospadias; 5-Alpha-reductase deficiency; 5 alpha reductase 2 deficiency; 5-alpha reductase deficiency; 5-alpha Reductase Deficiency; 5-ards; Maria mario syndrome; Maria-mario syndrome; Mario maria syndrome; Mario-maria syndrome; 5ARD; 5-ARD; 5α-reductase deficiency; 5α-reductase type 2 deficiency; 5α-reductase type II deficiency; 5α-Reductase type II deficiency; Congenital 5α-reductase deficiency; 5-alpha-reductase deficiency; 5α-Reductase deficiency; Congenital 5α-reductase type 2 deficiency; 5α-Reductase type 2 deficiency
5α-Reductase 2 deficiency (5αR2D) is an autosomal recessive condition caused by a mutation in SRD5A2, a gene encoding the enzyme 5α-reductase type 2 (5αR2). The condition is rare, affects only genetic males, and has a broad spectrum of presentations, most apparent in the genitalia where a male is born with an underdeveloped penis that might develop to various extents in puberty and hence be raised as female up to a certain age.
5α-Reductase inhibitor
CLASS OF MEDICATIONS WITH ANTIANDROGENIC EFFECTS USED PRIMARILY IN THE TREATMENT OF ENLARGED PROSTATE AND SCALP HAIR LOSS
5-alpha reductase inhibitors; 5-alpha reductase inhibitor; 5α-reductase inhibitor; 5a-reductase inhibitor; 5alpha-reductase inhibitor; 5alpha reductase inhibitor; 5a reductase inhibitor; 5A reductase inhibitor; 5A Reductase inhibitor; 5a Reductase inhibitor; 5a-Reductase inhibitor; 5alpha-Reductase inhibitor; 5alpha Reductase inhibitor; 5A-Reductase inhibitor; 5-alpha Reductase inhibitor; 5-alpha-Reductase inhibitor; 5 alpha-Reductase inhibitor; 5α reductase inhibitor; 5α Reductase inhibitor; 5 alpha Reductase inhibitor; 5 alpha reductase inhibitor; 5 alpha-reductase inhibitor; 5-a Reductase inhibitor; 5-a reductase inhibitor; 5 a reductase inhibitor; 5 a Reductase inhibitor; 5 a-Reductase inhibitor; 5 a-reductase inhibitor; 5-a-reductase inhibitor; 5-a-Reductase inhibitor; 5 α reductase inhibitor; 5 α Reductase inhibitor; 5 α-Reductase inhibitor; 5 α-reductase inhibitor; 5-α-reductase inhibitor; 5-α-Reductase inhibitor; 5-α Reductase inhibitor; 5-α reductase inhibitor; 5α-reductase inhibitors; 5-alpha-reductase inhibitor; 5ARI; 5α-Reductase inhibitors; DHT blockers; Dihydrotestosterone blockers; 5-alpha-Reductase Inhibitors
5α-Reductase inhibitors (5-ARIs), also known as dihydrotestosterone (DHT) blockers, are a class of medications with antiandrogenic effects which are used primarily in the treatment of enlarged prostate and scalp hair loss. They are also sometimes used to treat excess hair growth in women and as a component of hormone therapy for transgender women.
