TLC is an American girl group formed in Atlanta, Georgia, in 1990. The group's best-known line-up was composed of Tionne "T-Boz" Watkins, Lisa "Left Eye" Lopes and Rozonda "Chilli" Thomas. The group enjoyed success during the 1990s, with nine top-ten hits on the Billboard Hot 100, including four number-one singles: "Creep", "Waterfalls", "No Scrubs", and "Unpretty". The group also recorded four multi-platinum albums, including CrazySexyCool (1994), which received a diamond certification from the Recording Industry Association of America (RIAA). TLC also became the first R&B group in history to receive the Million certification from the Recording Industry Association of Japan (RIAJ) for FanMail (1999).

Having sold over 95 million records worldwide, TLC is the best-selling American girl group. VH1 ranked TLC as the greatest female group, placing them at number 12 on the list of 100 Greatest Women in Music. Billboard magazine ranked TLC as one of the greatest musical trios, as well as the seventh-most-successful act of the 1990s. The group's accolades include four career Grammy Awards, five MTV Video Music Awards, and five Soul Train Music Awards.

Twenty years after their debut, TLC was honored with an award called Outstanding Contribution to Music at the 17th MOBO Awards and with the Legend Award at the 2013 MTV Video Music Awards Japan. Following Lopes's death in 2002, instead of replacing her, the remaining members chose to continue as a duo. In 2017, they released their eponymous fifth album TLC. In 2022, the group was inducted into the Black Music & Entertainment Walk of Fame.