Allogamy or cross-fertilization is the fertilization of an ovum from one individual with the spermatozoa of another. By contrast, autogamy is the term used for self-fertilization. In humans, the fertilization event is an instance of allogamy. Self-fertilization occurs in hermaphroditic organisms where the two gametes fused in fertilization come from the same individual. This is common in plants (see Sexual reproduction in plants) and certain protozoans.

In plants, allogamy is used specifically to mean the use of pollen from one plant to fertilize the flower of another plant and usually synonymous with the term "cross-fertilization" or "cross-pollination" (outcrossing). The latter term can be used more specifically to mean pollen exchange between different plant strains or even different plant species (where the term cross-hybridization can be used) rather than simply between different individuals.

Parasites having complex life cycles can pass through alternate stages of allogamous and autogamous reproduction, and the description of a hitherto unknown allogamous stage can be a significant finding with implications for human disease.