d"indole - определение. Что такое d"indole
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Что (кто) такое d"indole - определение

CHEMICAL REACTION
Bischler-Mohlau indole synthesis; Bischler-Moehlau indole synthesis; Bischler-Möhlau indole synthesis; Bischler–Mohlau indole synthesis

Indole alkaloid         
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  • Methylergometrine maleate (Methergin)
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  • [[Pierre Joseph Pelletier]] (1788–1842), discoverer of [[strychnine]] and one of the founders of [[alkaloid]] chemistry
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  • Tryptamine (left) and phenethylamine (right) moieties of the lysergic acid molecule
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CLASS OF ALKALOIDS
Indole alkaloids
Indole alkaloids are a class of alkaloids containing a structural moiety of indole; many indole alkaloids also include isoprene groups and are thus called terpene indole or secologanin tryptamine alkaloids. Containing more than 4100 known different compounds, it is one of the largest classes of alkaloids.
indole         
  • Baeyer's original structure for indole, 1869
  • 2-position lithiation of indole
  • The Fischer indole synthesis
  • Synthesis of gramine from indole
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  • Example of a cycloaddition of indole
  • Oxidation of indole by ''N''-bromosuccinimide
  • The Vilsmeyer–Haack formylation of indole
  • Formation and reactions of the indole anion
  • Reaction of [[aniline]] and [[ethylene glycol]] to give indole.
  • The Leimgruber–Batcho indole synthesis
  • One-pot microwave-assisted synthesis of indole from phenylhydrazine and pyruvic acid
  • Indole is produced via anthranilate and reacts further to give the amino acid tryptophan.
CHEMICAL COMPOUND
Indoles; Indoyl; Indolic; Indol; Indolyl; 1-benzazole; 2,3-benzopyrrole; Ketole; Indoleic acid; Indole ring; Benzazol; Benzopyrrol
['?nd??l]
¦ noun Chemistry a crystalline organic compound with an unpleasant odour, present in coal tar and in faeces.
Origin
C19: blend of indigo (because obtained artificially from indigo blue) and L. oleum 'oil'.
Indoles         
  • Baeyer's original structure for indole, 1869
  • 2-position lithiation of indole
  • The Fischer indole synthesis
  • Synthesis of gramine from indole
  • center
  • Example of a cycloaddition of indole
  • Oxidation of indole by ''N''-bromosuccinimide
  • The Vilsmeyer–Haack formylation of indole
  • Formation and reactions of the indole anion
  • Reaction of [[aniline]] and [[ethylene glycol]] to give indole.
  • The Leimgruber–Batcho indole synthesis
  • One-pot microwave-assisted synthesis of indole from phenylhydrazine and pyruvic acid
  • Indole is produced via anthranilate and reacts further to give the amino acid tryptophan.
CHEMICAL COMPOUND
Indoles; Indoyl; Indolic; Indol; Indolyl; 1-benzazole; 2,3-benzopyrrole; Ketole; Indoleic acid; Indole ring; Benzazol; Benzopyrrol
·noun Natural disposition; natural quality or abilities.

Википедия

Bischler–Möhlau indole synthesis

The Bischler–Möhlau indole synthesis, also often referred to as the Bischler indole synthesis, is a chemical reaction that forms a 2-aryl-indole from an α-bromo-acetophenone and excess aniline; it is named after August Bischler and Richard Möhlau .

Despite its long history, this classical reaction had received relatively little attention in comparison with other methods for indole synthesis, owing to the reactions harsh conditions, poor yields and unpredictable regioselectivity. Recently, milder methods have been developed, including the use of lithium bromide as a catalyst and an improved procedure involving the use of microwave irradiation.