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Что (кто) такое l-dopa - определение

CHEMICAL COMPOUND

L-Dopa; L-dopa; El dopa; L Dopa; Levodopa; Eldopa; L-dihydroxyphenylalanine; ATC code N04BA01; ATCvet code QN04BA01; 3,4-dihydroxy-L-phenylalanine; Bendopa; Brocadopa; Cidandopa; Deadopa; Dopaflex; Dopaidan; Dopal; Dopal-Fher; Dopalina; Dopar; Doparkine; Doparl; Dopasol; Dopaston; Dopastral; Doprin; Eldopal; Eldopar; Eldopatec; Eurodopa; Helfo-Dopa; Insulamina; Laradopa; Larodopa; Ledopa; Levedopa; Levopa; Maipedopa; Pardopa; Prodopa; Syndopa; Veldopa; Weldopa; 3,4-dihydroxyphenylalanine; Levadopa; CVT-301; Inbrija

l-dopa

¦ noun Biochemistry see dopa.

levodopa

[?li:v?(?)'d??p?]

¦ noun another term for l-dopa.

dopa

WIKIMEDIA DISAMBIGUATION PAGE

DOPA; Dopa (disambiguation)

['d??p?]

¦ noun Biochemistry a compound which is present in nerve tissue as a precursor of dopamine (especially as the laevorotatory form l-dopa) and is used to treat Parkinsonism.

Origin

early 20th cent.: from Ger., acronym from the systematic name dihydroxyphenylalanine.

Википедия

L-DOPA

l-DOPA, also known as levodopa and l-3,4-dihydroxyphenylalanine, is an amino acid that is made and used as part of the normal biology of some plants and animals, including humans. Humans, as well as a portion of the other animals that utilize l-DOPA, make it via biosynthesis from the amino acid l-tyrosine. l-DOPA is the precursor to the neurotransmitters dopamine, norepinephrine (noradrenaline), and epinephrine (adrenaline), which are collectively known as catecholamines. Furthermore, l-DOPA itself mediates neurotrophic factor release by the brain and CNS. l-DOPA can be manufactured and in its pure form is sold as a psychoactive drug with the INN levodopa; trade names include Sinemet, Pharmacopa, Atamet, and Stalevo. As a drug, it is used in the clinical treatment of Parkinson's disease and dopamine-responsive dystonia.

l-DOPA has a counterpart with opposite chirality, d-DOPA. As is true for many molecules, the human body produces only one of these isomers (the l-DOPA form). The enantiomeric purity of l-DOPA may be analyzed by determination of the optical rotation or by chiral thin-layer chromatography.

https://en.wikipedia.org/wiki/L-DOPA

Примеры употребления для l-dopa

1. To date, the most commonly used Parkinsons drug has been L–Dopa, which only controls the symptoms for most patients.

2. In 1'6' the neurologist Dr Oliver Sacks used the then new drug L–Dopa to awaken a group of catatonic patients who had survived the 1'17–1'28 epidemic of the mysterious "sleeping disease", known as encephalitis lethargica.

3. It has now been proved that tamoxifen can also prevent breast cancer in high–risk women. '. Parkinson‘s disease Parkinson‘s Disease, which causes slowness and absence of movement as well as tremor and rigidity, can be treated with the drug l–dopa, but its initial effects do not last.