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Что (кто) такое multiforme - определение
![[[Histopathology]] of glioblastoma, showing high grade astrocytoma features of marked nuclear pleomorphism, multiple mitoses (one at white arrow) and multinucleated cells (one at black arrow), with cells having a patternless arrangement in a pink fibrillary background on H&E stain.](https://commons.wikimedia.org/wiki/Special:FilePath/Histopathology of glioblastoma, high magnification, annotated.jpg?width=200 "[[Histopathology]] of glioblastoma, showing high grade astrocytoma features of marked nuclear pleomorphism, multiple mitoses (one at white arrow) and multinucleated cells (one at black arrow), with cells having a patternless arrangement in a pink fibrillary background on H&E stain.")
![Lower magnification histopathology, showing necrosis surrounded by [[pseudopalisade]]s of tumor cells, conferring a diagnosis of glioblastoma rather than [[anaplastic astrocytoma]]](https://commons.wikimedia.org/wiki/Special:FilePath/Glioblastoma (1).jpg?width=200 "Lower magnification histopathology, showing necrosis surrounded by [[pseudopalisade]]s of tumor cells, conferring a diagnosis of glioblastoma rather than [[anaplastic astrocytoma]]")
Википедия
Erythema multiforme (EM) is a skin condition that appears with red patches evolving into target lesions, typically on both hands.
It is a type of erythema possibly mediated by deposition of immune complexes (mostly IgM-bound complexes) in the superficial microvasculature of the skin and oral mucous membrane that usually follows an infection or drug exposure. It is an uncommon disorder, with peak incidence in the second and third decades of life. The disorder has various forms or presentations, which its name reflects (multiforme, "multiform", from multi- + formis). Target lesions are a typical manifestation. Two types, one mild to moderate and one severe, are recognized (erythema multiforme minor and erythema multiforme major).
Erythema multiforme was first described by von Hebra in 1860.
