nucleotide - определение. Что такое nucleotide
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Что (кто) такое nucleotide - определение

BIOLOGICAL MOLECULES THAT FORM THE BUILDING BLOCKS OF NUCLEIC ACIDS
Nucleotides; Salvage synthesis; Genetic code (ATGC); Deoxynucleotide triphosphate; Deoxynucleotides-triphosphate; Thionucleotides; Nucleotide mapping; Nucleotide transport proteins; Nucleatide; Riboneucleotide; Dinucleotide; Nucleotide metabolism; Nucleoside monophosphate; Deoxynucleoside triphosphate; Nucleotide synthesis; Nucleoside diphosphate; Biosynthesis of nucleotides; Tetranucleotide; 5'nucleotide; 5-nucleotide
  • Showing the arrangement of nucleotides within the structure of nucleic acids: At lower left, a monophosphate nucleotide; its nitrogenous base represents one side of a base-pair. At the upper right, four nucleotides form two base-pairs: thymine and adenine (connected by ''double'' hydrogen bonds) and guanine and cytosine (connected by ''triple'' hydrogen bonds). The individual nucleotide monomers are chain-joined at their sugar and phosphate molecules, forming two 'backbones' (a [[double helix]]) of nucleic acid, shown at upper left.
  • This nucleotide contains the five-carbon sugar [[deoxyribose]] (at center), a [[nucleobase]] called [[adenine]] (upper right), and one [[phosphate]] group (left). The deoxyribose sugar joined only to the nitrogenous base forms a <u title="Nucleotide">[[Deoxyribonucleoside]]</u>  called [[deoxyadenosine]], whereas the whole structure along with the phosphate group is a <u title="Deoxyadenosine monophosphate" href="deoxyadenosine monophosphate">nucleotide</u>, a constituent of DNA with the name [[deoxyadenosine monophosphate]].
  • 250px
  • pyrimidines]]—are sketched at right (in blue).
  • The synthesis of IMP. The color scheme is as follows: <span style="font-weight: bold;"><span style="color: blue;">enzymes</span>, <span style="color: rgb(219,155,36);">coenzymes</span>, <span style="color: rgb(151,149,45);">substrate names</span>, <span style="color: rgb(227,13,196);">metal ions</span>, <span style="color: rgb(128,0,0);">inorganic molecules</span> </span>
  • UMP]]'''.</div>The color scheme is as follows: <span style="font-weight: bold;"><span style="color: blue;">enzymes</span>, <span style="color: rgb(219,155,36);">coenzymes</span>, <span style="color: rgb(151,149,45);">substrate names</span>, <span style="color: rgb(128,0,0);">inorganic molecules</span> </span>

nucleotide         
¦ noun Biochemistry a compound consisting of a nucleoside linked to a phosphate group, forming the basic structural unit of nucleic acids.
Nucleotide         
Nucleotides are organic molecules consisting of a nucleoside and a phosphate. They serve as monomeric units of the nucleic acid polymers – deoxyribonucleic acid (DNA) and ribonucleic acid (RNA), both of which are essential biomolecules within all life-forms on Earth.
Single-nucleotide polymorphism         
  • '''Associations between SNPs, methylation patterns and gene expression of biological traits'''
  • Types of single-nucleotide polymorphism (SNPs)
SINGLE NUCLEOTIDE POSITION IN GENOMIC DNA AT WHICH DIFFERENT SEQUENCE ALTERNATIVES EXIST
SNPs; Single nucleotide polymorphisms; Single Nucleotide Polymorphism; Polymorphic DNA; SNiP technique; Single-nucleotide polymorphisms; SNP mutation; Single nucleotide polymorphism; Singlenucleotide polymorphisms; Single nucleotide polymorphic; Single-nucleotide polymorphic; Singlenucleotide polymorphic; Single Nucleotide Polymorphisms; SNP detection; Single nucleotide DNA variation; Single nucleotide variants; Single-nucleotide DNA variation; Single base-pair polymorphism; Single-Nucleotide Polymorphism; Single nucleotide variant; Single-nucleotide variant; Single-nucleotide variation; Single-nucelotide polymorphism
In genetics, a single-nucleotide polymorphism (SNP ; plural SNPs ) is a germline substitution of a single nucleotide at a specific position in the genome. Although certain definitions require the substitution to be present in a sufficiently large fraction of the population (e.

Википедия

Nucleotide

Nucleotides are organic molecules composed of a nitrogenous base, a pentose sugar and a phosphate. They serve as monomeric units of the nucleic acid polymers – deoxyribonucleic acid (DNA) and ribonucleic acid (RNA), both of which are essential biomolecules within all life-forms on Earth. Nucleotides are obtained in the diet and are also synthesized from common nutrients by the liver.

Nucleotides are composed of three subunit molecules: a nucleobase, a five-carbon sugar (ribose or deoxyribose), and a phosphate group consisting of one to three phosphates. The four nucleobases in DNA are guanine, adenine, cytosine and thymine; in RNA, uracil is used in place of thymine.

Nucleotides also play a central role in metabolism at a fundamental, cellular level. They provide chemical energy—in the form of the nucleoside triphosphates, adenosine triphosphate (ATP), guanosine triphosphate (GTP), cytidine triphosphate (CTP) and uridine triphosphate (UTP)—throughout the cell for the many cellular functions that demand energy, including: amino acid, protein and cell membrane synthesis, moving the cell and cell parts (both internally and intercellularly), cell division, etc. In addition, nucleotides participate in cell signaling (cyclic guanosine monophosphate or cGMP and cyclic adenosine monophosphate or cAMP), and are incorporated into important cofactors of enzymatic reactions (e.g. coenzyme A, FAD, FMN, NAD, and NADP+).

In experimental biochemistry, nucleotides can be radiolabeled using radionuclides to yield radionucleotides.

5-nucleotides are also used in flavour enhancers as food additive to enhance the umami taste, often in the form of a yeast extract.

Примеры употребления для nucleotide
1. It looked at genetic variations called single nucleotide polymorphisms.
2. NCBI is host to the GenBank nucleotide sequence database.
3. The International Nucleotide Sequence Database Collaboration (INSDC) has realized the vision of the researchers who initiated the sequence database projects by making the global sharing of nucleotide sequence information possible." Graham Cameron, Associate Director of EMBL‘s European Bioinformatics Institute, added "This is an important milestone in the history of the nucleotide sequence databases.
4. The human genome consists of 3.1 billion nucleotide pairs, strung together in a particular order.
5. Each person‘s collection of these changes (called "single nucleotide polymorphisms, or SNPs) contributes to his or her individuality.