Mi-2/NuRD complex
AN APPROXIMATELY 2 MDA MULTI-SUBUNIT COMPLEX THAT EXHIBITS ATP-DEPENDENT CHROMATIN REMODELING ACTIVITY IN ADDITION TO HISTONE DEACETYLASE (HDAC) ACTIVITY, AND HAS BEEN SHOWN TO ESTABLISH TRANSCRIPTIONAL REPRESSION OF A NUMBER OF TARGET GENES IN VERTE
NuRD; NURD; Nucleosome Remodelling Deacetylase; Nucleosome Remodelling Deacetylase complex; Mi-2 complex
In the field of molecular biology, the Mi-2/NuRD (Nucleosome Remodeling Deacetylase) complex, is a group of associated proteins with both ATP-dependent chromatin remodeling and histone deacetylase activities. , Mi-2/NuRD was the only known protein complex that couples chromatin remodeling ATPase and chromatin deacetylation enzymatic functions.