Point and click are the actions of a computer user moving a pointer to a certain location on a screen (pointing) and then pressing a button on a mouse, usually the left button (click), or other pointing device. An example of point and click is in hypermedia, where users click on hyperlinks to navigate from document to document.

Point and click can be used with any number of input devices varying from mouses, touch pads, trackpoint, joysticks, scroll buttons, and roller balls.

User interfaces, for example graphical user interfaces, are sometimes described as "point-and-click interfaces", often to suggest that they are very easy to use, requiring that the user simply point to indicate their wishes. These interfaces are sometimes referred to condescendingly (e.g., by Unix users) as "click-and-drool" or "point-and-drool" interfaces.

The use of this phrase to describe software implies that the interface can be controlled solely through the mouse (or some other means such as a stylus), with little or no input from the keyboard, as with many graphical user interfaces.

In some systems, such as Internet Explorer, moving the pointer over a link (or other GUI control) and waiting for a split-second (that can range from 0.004 to 0.7 s) can cause a tooltip to be displayed.