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RICE is a mnemonic acronym for the four elements of a treatment regimen that was once recommended for soft tissue injuries: rest, ice, compression, and elevation. It was considered a first-aid treatment rather than a cure and aimed to control inflammation. It was thought that the reduction in pain and swelling that occurred as a result of decreased inflammation helped with healing. The protocol was often used to treat sprains, strains, cuts, bruises, and other similar injuries.
The mnemonic was introduced by Dr. Gabe Mirkin in 1978. He took back his support of this regimen in 2014 after learning of the role of inflammation in the healing process. The implementation of RICE for soft tissue injuries as described by Dr. Mirkin is no longer recommended, as there is not enough research on the efficacy of RICE in the promotion of healing. In fact, many components of the protocol has since been shown to impair or delay healing by inhibiting inflammation. Early rehabilitation is now the recommendation to promote healing. Ice, compression, and elevation may have roles in decreasing swelling and pain, but have not shown to help with healing an injury.
There are different variations of the protocol, which may emphasize additional protective actions. However, these variations similarly lack sufficient evidence to be broadly recommended. Examples include PRICE, POLICE, and PEACE & LOVE.