Löffler (literally "Spooner") is a German language surname. It is often anglicised as Loeffler. In most cases, the name originates from people who produced and/or traded spoons (German: löffel). Notable people with the surname include:

• Anna Seelig-Löffler (born 1944), Swiss chemist
• August Löffler (1822–1866), German painter
• Charles Martin Loeffler (1861–1935), German-born American composer
• Cullen Loeffler (born 1981), American football player
• Diane Loeffler (1953–2019), American politician from Minnesota
• Douglas Loeffler (born 1932), American politician from Florida
• Frank Löffler (born 1980), German ski jumper
• Friedrich Löffler (1852–1915), German bacteriologist
• Gerold Löffler, Swiss bobsledder
• Karl Löffler, head of the Jewish Affairs department of the Gestapo in Cologne, Germany during the 1930s and 1940s
• Kelly Loeffler (born 1970), American businesswoman and politician
• Ken Loeffler (1902–1975), American basketball coach
• Leopold Loeffler (1827–1898), Polish painter
• Louis R. Loeffler (1897–1972), American film editor
• Louise Loeffler, Belgian chess master
• Margot Klestil-Löffler (born 1954), Austrian diplomat
• Pete Loeffler (born 1976), American guitarist and singer
• Scot Loeffler (born 1974), American football coach
• Tom Loeffler (born 1946), American politician from Texas
• Wilhelm Löffler (doctor) (born 1887), Swiss physician