Wasserman or Wassermann is a surname. Notable people with the surname include:

• Aaron E. Wasserman (1920–2015), American food scientist
• Aharon Wasserman (born 1986), American entrepreneur and software designer
• Al Wasserman (born 1921), American film maker
• Anatoly Wasserman (born 1952), Russian journalist and political pundit
• Antony Wassermann (born 1957), British mathematician
• August von Wassermann (1866–1925), German bacteriologist
• Bob Wasserman (1934–2011), American politician and police chief, Mayor of Fremont, California
• Cale Wassermann (born 1983), American soccer coach
• Casey Wasserman (born 1974), American entertainment executive and owner of the Los Angeles Avengers
• Dale Wasserman (1914–2008), American playwright
• Dan Wasserman, American political cartoonist
• Dave Wasserman (born 1984), American political analyst
• Debbie Wasserman Schultz (born 1966), American politician from Florida
• Dora Wasserman (1919–2003), actress and founder of the Dora Wasserman Yiddish Theatre in Montreal
• Edward Wasserman, American professor of psychology at the University of Iowa
• Ehren Wassermann (born 1980), American baseball pitcher
• Elchonon Wasserman (1874–1941), Lithuanian rabbi and rosh yeshiva
• Eva Wasserman-Margolis, American composer, conductor and clarinet player
• Gordon Wasserman, Baron Wasserman (born 1938), member of the UK House of Lords
• Harvey Wasserman (born 1945), American journalist
• Jack Wasserman (1927–1977), Canadian newspaper columnist
• Jakob Wassermann (1873–1934), German writer and novelist
• James Wasserman (1948–2020), American author and occultist
• Jeffrey Wasserman (1946–2006), American artist
• Jerry Wasserman (born 1945), American actor
• John L. Wasserman (1938–1979), American entertainment critic for the San Francisco Chronicle from 1964 – 1979
• Kathryn Wasserman Davis (1907–2013), American philanthropist and foundation executive
• Kevin 'Noodles' Wasserman (born 1963), American lead guitarist and background vocalist for The Offspring
• Kimberly Wasserman, American environmentalist
• Larry A. Wasserman, Canadian statistician
• Lew Wasserman (1913–2002), American film and entertainment agent and studio executive
• Mel Wasserman (1932–2002), American businessman, entrepreneur and founder of CEDU Education
• Noam T. Wasserman, American academic
• Oscar Wassermann (1869–1934), German banker
• Paul Wasserman (1934–2007), American entertainment publicist
• Philip Wasserman (1828–1895), mayor of Portland, Oregon
• Rick D. Wasserman (born 1973), American actor
• Rob Wasserman (1952–2016), American composer and bass player
• Robert Wasserman (disambiguation), several people
• Robin Wasserman (born 1978), American novelist
• Ron Wasserman (born 1961), American composer
• Ruth Wasserman Lande (born 1976), Israeli diplomat, lecturer and social activist
• Sandra Wasserman (born 1970), Belgian tennis player
• Sheldon Wasserman (born 1961), Wisconsin State Assembly member
• Simcha Wasserman (1899–1992), Rabbi/Educator, founder of several schools (France, USA, Israel)
• Stanley Wasserman (born 1951), American statistician
• Suzanne Wasserman (1957–2017), American film director, historian and writer
• Tony Wasserman, American computer scientist
• Václav Wasserman (1898–1967), Czechoslovak screenwriter, film actor and director
• Wald Wassermann (born 1972), Belgian-born American physicist
• Walter Wassermann (1883–1944), German screenwriter
• Zbigniew Wassermann (1949–2010), Polish politician