İskenderun (Arabic: إسكندرونة), historically known as Alexandretta (Greek: Αλεξανδρέττα, lit. little Alexandria) and Scanderoon, is a city in Hatay Province on the Mediterranean coast of Turkey. Located on an alluvial plain, the city was heavily damaged by powerful earthquakes in February 2023 and subsequent aftershocks, floods and fires.

The city's history dates back to 333 BC, when it was founded by Alexander the Great as Alexandretta. It subsequently fell under Seleucid rule before being conquered by the Romans. After defeating the Byzantines in the 8th century, the Abbasid Caliphate gained control of the city. During the First Crusade, it came under the control of the Principality of Antioch before being captured by the Mamluk Sultanate.

By the 15th century, the Ottomans had conquered the city, maintaining control over it until the partition of the Ottoman Empire after the Allied victory in World War I. It subsequently became a sanjak in the French mandate of Syria until 1938, when France granted the region independence. The city became part of the Hatay State which in turn united with Turkey in 1939.